Synthesis and biological activity of 3-vinylthio- and 3-vinylthiomethylcephem derivatives.

نویسندگان

  • S Nishimura
  • N Yasuda
  • H Sasaki
  • K Kawabata
  • K Sakane
  • T Takaya
چکیده

The synthesis and biological properties of some 3-vinylthio- and 3-vinylthiomethylcephem derivatives are described. Both series possess potent antibacterial activity. Among them, 3-[(Z)-2-cyanovinylthiomethyl]cephem derivative was found to have an expanded antibacterial spectrum.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 43 9  شماره 

صفحات  -

تاریخ انتشار 1990